• TARDBPTAR DNA binding protein
  • Detail information

    Gene Symbol TARDBP
    Full name TAR DNA binding protein
    Synonym TDP-43
    Genome position chromosome: 1; Location: 1p36.22
    11072678 .. 11085548 (strand : +)
    Links EntrezGene
    UCSC
    OMIM

    The GRCh37/hg19 sequence assembly is used for the human genomic reference sequence.
  • Sequence information

    Exon : Intron 100:1 50:1 10:1 3:1 1:1   Age onset & duration hide show

    expanded image




    a.a. : NP_031401.1

    mRNA : NM_007375.3
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  • Mutation & Clinical information

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  • Multiple alignments

    Multiple alignments of all patients' sequences   (Registration is needed to see this information, because unpublished data is contained.)

    Multiple alignments of orthologous sequences
  • 3D structure

    show 1wf0.pdb
  • Structure information

    Exon Start AA End AA Structure
    1, 2, 3, 4, 5 1 414 Chain
    2, 3, 4 104 200 Domain
    4, 5 191 262 Domain
    5 274 413 Compositionally biased region
    2 91 91 Modified residue
    2 92 92 Modified residue
    2, 3 106 175 Mutagenesis site
    2 106 111 Mutagenesis site
    2 106 111 Mutagenesis site
    3 147 149 Mutagenesis site
    4, 5 193 257 Mutagenesis site
    2 106 110 Strand
    2 117 124 Helix
    2 125 127 Helix
    2, 3 130 137 Strand
    3 139 141 Strand
    3 143 154 Strand
    3 155 163 Helix
    3 166 168 Strand
    3 171 176 Strand
    4 193 197 Strand
    4 200 202 Strand
    4 204 210 Helix
    4 212 214 Turn
    4 219 221 Strand
    4 231 233 Strand
    4, 5 237 242 Helix
    5 243 245 Turn
    5 247 250 Strand
    5 253 258 Strand
  • Overview of mutations

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